Superoxide Dismutase（SOD，EC1.15.1.1) deals with the superoxide radical by alternately adding or removing an electron from the superoxide molecules it encounters. Based on the metalion cofactor identified in their active site, four types of SODs (Cu/Zn-SOD, Fe-SOD, Mn-SOD and Ni- SOD) are reported. Mn-SOD is presented in the mitochondria of eukaryotic cells and prokaryotic cells. The animal-free Mn-SOD with higher purity and activity is expressed by E. coli.

Biochemical Research: SOD is a unique enzyme which can eliminate superoxide radical, thus protecting the cell from superoxide toxicity. SOD is widely used for adjusting endocrine system and immunity enhancement, in clinical and research of inflammation, such as therapy rheumatoid arthritis, Multiple chronic arthritis, myocardial infarction, angiocardiopathy, cancer patients.

Product description:

Appearance: White powder, lyophilized

Preservation solution:100mM phosphate buffer，pH7.4

Specific Activity:15,528 U/mg protein

Unit Definition: pH8.2, 54 mM Tris-Cl 140 uL, including 54 mM Dimethyl swollen acid sodium, 1.07 mM diethylenetriamine pentaacetic acid, 5 uLddH2O or ( 5uL pyrogallic acid in10 mM HCI); total reaction volume is 150 uL, timekeeping. The autoxidation rate is effective within 3 minutes，controlling the quantity of pyrogallic acid, keeping the autoxidation rate will produce a increase per min by 0.018 at 420 nm min，and produce a increase per min by 0.010 after SOD adding.

Basic information:

Source: Recombinant expression

Molecular weight: About 26kDa (SDS-PAGE detection)

Purity:≥90% (SDS-PAGE test)

Storage: 4℃, store at -20℃ for long-term preservation

Transportation: Cold packs  

Function and Application:

1. It is a natural scavenger of oxygen free radicals in organism, which has a wide range of medical value and can be used in medicine, food and as an additive in daily chemical products.

2. It has been approved for clinical use and has shown strong regenerative repair ability to some of the tissues and fibrosis caused by age, disease, or injury.

3. It has been successfully applied to adjuvant therapy after radiotherapy, to control the progression of heart disease, and to treat severe rheumatoid arthritis.

4. It is widely used in cosmetic additives, such as the use of superoxide dismutase SOD mask, SOD honey, SOD snake powder and other cosmetics, there are not less than hundreds of products.

5. It is used as a food supplement, people find feasible way to maintain a high level of SOD in the human body, which is in the consumption of food at the same time, to provide adequate nutrition for the synthesis of liver SOD, or directly to the exogenous SOD wrapped in food protein, through the digestive system without being digested into the other position of the bod